反应详情

温度

40 °C

The reaction of 3-methoxybenzyl isothiocyanate with 3-methoxybenzyl amine in ethanol was repeated doubling the reaction volume and reactants and heating for 2 h at 40° C. Crystallization at −10° C., followed by evaporation of the supernatant to 20 ml and a second crystallization gave 98.4% of the theoretical yield for the two crystallizations combined. Calculated elemental analysis of 3-methoxybenzyl thiourea: C, 64.53; H, 6.37; N, 8.85; S, 10.13. Found: C, 64.30; H, 6.46; N, 8.85; S, 10.09.

1. customCrystallization at −10° C.
2. customfollowed by evaporation of the supernatant to 20 ml
3. customa second crystallization
4. customgave 98.4% of the
5. customtheoretical yield for the two crystallizations