反应详情

Methoxylamine (9.00 g (108 mmol) was suspended in pyridine (30.0 ml). To this, under cooling with ice and with stirring, p-toluenesulfonyl chloride (19.07 g (100 mmol)) was added and the mixture was stirred under cooling with ice for 30 minutes and at room temperature for 2 hours. Water (200.0 ml) was added to the reaction mixture to bring about separation of crystals. After 30 minutes' stirring, the crystals were filtered and washed to give 20.26 g (99%) of N-methoxy-p-toluenesulfonamide as white crystals.

1. temperatureTo this, under cooling with ice
2. stirringthe mixture was stirred
3. customto bring about separation of crystals
4. stirringAfter 30 minutes' stirring
5. filtrationthe crystals were filtered
6. washwashed