Sodium Carbonate → HCID 86759053, compound

HRID 1356780Notes

Reaction equation

HRID 1356780 reaction equation
[CH3:1][C:2]([CH3:11])([CH3:10])[C:3]#[C:4][CH:5]=[CH:6][CH2:7][NH:8][CH3:9].C(=O)([O-])[O-].[Na+].[Na+].Br[CH2:19][C:20]1[CH:21]=[C:22]([C:26](=[O:28])[CH3:27])[CH:23]=[CH:24][CH:25]=1>>[CH3:1][C:2]([CH3:11])([CH3:10])[C:3]#[C:4]/[CH:5]=[CH:6]\[CH2:7][N:8]([CH2:19][C:20]1[CH:21]=[C:22]([C:26](=[O:28])[CH3:27])[CH:23]=[CH:24][CH:25]=1)[CH3:9]

Participants

4

Reactant 3

HCID 10340Sodium CarbonateHCID 154798071-(3-(Bromomethyl)phenyl)ethan-1-oneHCID 53427009N,6,6-trimethylhept-2-en-4-yn-1-amine

Product 1

HCID 86759053HCID 86759053, compoundYield 14.8%

Procedure

The procedure described in Example 1 was repeated, except that N-(6,6-dimethyl-2-hepten-4-ynyl)methylamine (trans:cis=about 3:1) (17.7 g; 116.8 mmol), sodium carbonate (17.7 g; 166.8 mmol), and 3′-bromomethylacetophenone (23.7 g; 111.2 mmol) were used, to thereby yield 4.67 g of the target compound (yield: 14.8%).

Sources & evidence

ORD record
ord-4e1cbbb16be4414a9fc79c44797deb0f
Source dataset
uspto-grants-2003_07
Patent number
US06586633B1

Reaction notes

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