HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylamine hydrochloride → 3'-(N-Ethylaminomethyl)acetophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylamine hydrochloride | HCID 11198 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1-(3-(Bromomethyl)phenyl)ethan-1-one | HCID 15479807 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 3'-(N-Ethylaminomethyl)acetophenone | HCID 18509490 | 66.7% |
Reaction Steps
The procedure described in Referential Example 4 was repeated, except that ethylamine hydrochloride (16.31 g; 200 mmol), sodium hydroxide (instead of triethylamine) (8 g; 200 mmol), and 3′-bromomethylacetophenone (4.26 g; 20 mmol) were used, to thereby yield 2.36 g of the target compound (yield: 66.7%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586633B1 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-6495665b67df4ae2bce83b3239720d0a |
| Source note | uspto-grants-2003_07 |