Ethyl Acetate → HCID 12082818, compound

HRID 1356897Notes

Reaction equation

HRID 1356897 reaction equation
F[CH2:2][C:3]1[CH:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:5]([C:14]2[CH:19]=[CH:18][C:17]([S:20]([NH2:23])(=[O:22])=[O:21])=[CH:16][CH:15]=2)[N:4]=1.C(OCC)(=[O:26])C>O=[Mn]=O>[CH:2]([C:3]1[CH:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:5]([C:14]2[CH:19]=[CH:18][C:17]([S:20]([NH2:23])(=[O:22])=[O:21])=[CH:16][CH:15]=2)[N:4]=1)=[O:26]

Participants

4

Reactant 2

HCID 8857Ethyl AcetateHCID 10520508HCID 10520508, compound

Product 1

HCID 12082818HCID 12082818, compound

Reagents, catalysts & solvents 1

HCID 14801Manganese dioxideCatalyst

Procedure

To a solution of the alcohol prepared in Example 131, Step 3 (1.1 g, 3.3 mmol) in ethyl acetate (20 mL) was added MnO2 (5 g, 60 mmol) and the mixture stirred at room temperature overnight. The mixture was filtered through Celite and the solution was concentrated to provide the crude aldehyde.

Workup

  1. filtrationThe mixture was filtered through Celite
  2. concentrationthe solution was concentrated

Sources & evidence

ORD record
ord-3acaff66fec440ce8672de5e5c5fe5a8
Source dataset
uspto-grants-2003_07
Patent number
US06586603B1

Reaction notes

Loading…