HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → 4-(3-Nitrophenyl)morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 1-Fluoro-3-nitrobenzene | HCID 9823 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 4-(3-Nitrophenyl)morpholine | HCID 1253273 | — |
Reaction Steps
Using 1-fluoro-3-nitrobenzene (10 g, 0.07M) and morpholine (33.5 g, 0.38M) in DMSO (116 ml) is prepared using the method described by Brown G. R. et al., Tet. Lett. 40 (1999) 1219-1222. Filtration of the precipitated product yields the product; mp 113.8-115.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06589950B1 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-120c91f5d49349e2ba181f3c8ccb7679 |
| Source note | uspto-grants-2003_07 |