4-Chlorobenzenesulfonyl chloride → HCID 18504974, compound

HRID 1357002Notes

Reaction equation

HRID 1357002 reaction equation
C(N(CC)CC)C.[Cl:8][C:9]1[CH:14]=[CH:13][C:12]([S:15](Cl)(=[O:17])=[O:16])=[CH:11][CH:10]=1.[NH2:19][CH2:20][CH2:21][C:22]1[CH:28]=[CH:27][C:25]([NH2:26])=[CH:24][CH:23]=1>ClCCl>[NH2:26][C:25]1[CH:27]=[CH:28][C:22]([CH2:21][CH2:20][NH:19][S:15]([C:12]2[CH:13]=[CH:14][C:9]([Cl:8])=[CH:10][CH:11]=2)(=[O:17])=[O:16])=[CH:23][CH:24]=1

Participants

5

Reactant 3

HCID 73984-Chlorobenzenesulfonyl chlorideHCID 8471TriethylamineHCID 728952-(4-Aminophenyl)ethylamine

Product 1

HCID 18504974HCID 18504974, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

47.5 ml of triethylamine and then, in portions, 72 g of 4-chlorobenzenesulphonyl chloride, are added at ambient temperature to a solution of 46.5 g (340 mmol) of 4-(2-aminoethyl)aniline in a liter of dichloromethane. The mixture is then stirred for one night and subsequently filtered. The solid obtained is washed with water and dried using a dessicator to yield the expected product.

Workup

  1. filtrationsubsequently filtered
  2. customThe solid obtained
  3. washis washed with water
  4. customdried

Sources & evidence

ORD record
ord-2ce41509f4024369aae9ce6562557b84
Source dataset
uspto-grants-2003_07
Patent number
US06589956B2

Reaction notes

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