Thionyl Chloride → 3-Benzyloxy-4-methoxybenzoyl chloride

HRID 1357008Notes

Reaction equation

HRID 1357008 reaction equation
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH:15]=[CH:16][C:17]=1[O:18][CH3:19])[C:12](O)=[O:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:22])=O>>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH:15]=[CH:16][C:17]=1[O:18][CH3:19])[C:12]([Cl:22])=[O:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 940573-Benzyloxy-p-anisic acid

Product 1

HCID 109677953-Benzyloxy-4-methoxybenzoyl chlorideYield 98%

Procedure

Operating analogously to example 2 starting from 3-benzyloxy-4-methoxy benzoic acid (35.86 g, 0.139 moles) obtained as described in example 1, in thionyl chloride (150 ml), 35.01 g of the title product were obtained (yield: 98%).

Workup

  1. customobtained

Sources & evidence

ORD record
ord-fceea9f58b0046dab470beeac4ead0bc
Source dataset
uspto-grants-2003_07
Patent number
US06589951B1

Reaction notes

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