Benzoyl chloride → Ethyl 3-benzoylamino-3-(3-nitrophenyl)-propionate

HRID 1357068노트

반응식

HRID 1357068 반응식
Cl.[NH2:2][CH:3]([C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([N+:16]([O-:18])=[O:17])[CH:11]=1)[CH2:4][C:5]([O:7][CH2:8][CH3:9])=[O:6].[C:19](Cl)(=[O:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[C:19]([NH:2][CH:3]([C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([N+:16]([O-:18])=[O:17])[CH:11]=1)[CH2:4][C:5]([O:7][CH2:8][CH3:9])=[O:6])(=[O:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

참가 물질

3

반응물 2

HCID 7412Benzoyl chlorideHCID 16188861Ethyl 3-amino-3-(3-nitrophenyl)propanoate hydrochloride

생성물 1

HCID 3816281Ethyl 3-benzoylamino-3-(3-nitrophenyl)-propionate

실험 절차

Corresponding to Example 3a, 5.0 g of (1b) were acetylated by addition of benzoyl chloride. A white solid was obtained (yield: 3.3 g).

후처리

  1. customA white solid was obtained (yield: 3.3 g)

출처 및 근거

ORD 기록
ord-7d20bcdf9daf43d2aa44defe19281932
출처 데이터셋
uspto-grants-2003_07
특허 번호
US06589972B2

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