Lithium Hydroxide → HCID 178512553, compound

HRID 1357080Notes

Reaction equation

HRID 1357080 reaction equation
[NH:1]([C:5]1[CH:6]=[C:7]([S:11]([NH:14][C:15]2[CH:16]=[C:17]([CH2:21][CH:22]([NH:28][C:29](=[O:38])[CH2:30][CH2:31][C:32]3[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=3)[C:23]([O:25]CC)=[O:24])[CH:18]=[CH:19][CH:20]=2)(=[O:13])=[O:12])[CH:8]=[CH:9][CH:10]=1)[C:2]([NH2:4])=[NH:3].[OH-].[Li+]>>[NH:1]([C:5]1[CH:6]=[C:7]([S:11]([NH:14][C:15]2[CH:16]=[C:17]([CH2:21][CH:22]([NH:28][C:29](=[O:38])[CH2:30][CH2:31][C:32]3[CH:33]=[CH:34][CH:35]=[CH:36][CH:37]=3)[C:23]([OH:25])=[O:24])[CH:18]=[CH:19][CH:20]=2)(=[O:13])=[O:12])[CH:8]=[CH:9][CH:10]=1)[C:2]([NH2:4])=[NH:3]

Participants

3

Reactant 2

HCID 3939Lithium HydroxideHCID 178470927HCID 178470927, compound

Product 1

HCID 178512553HCID 178512553, compound

Procedure

Corresponding to Example 4, 410 mg of (6f) were hydrolysed using lithium hydroxide. A white solid was obtained (yield: 221 mg).

Workup

  1. customA white solid was obtained (yield: 221 mg)

Sources & evidence

ORD record
ord-2e1ed449b3494f92b79bc0bf94c641ff
Source dataset
uspto-grants-2003_07
Patent number
US06589972B2

Reaction notes

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