反应详情

K2CO3 (2.67 g) was added to a solution of methyl 3-oxononanoate (3.01 g) and methyl iodide (2.77 g) in acetone (100 ml) and the mixture was stirred at room temperature for 24 hours. The reaction solution was celite filtered, and then the mother liquor was concentrated under reduced pressure and the residue was purified by silica gel column chromatography (n-hexane/AcOEt=13/1) to obtain methyl 2-methyl-3-oxononanoate.

1. filtrationfiltered
2. concentrationthe mother liquor was concentrated under reduced pressure
3. customthe residue was purified by silica gel column chromatography (n-hexane/AcOEt=13/1)