Acetic Anhydride → HCID 86589721, compound

Participants

Reaction Steps

Pyridine (400 μl) and Ac2O (15 μl) were added to 6-(5-aminobenzofuran-2-yl)-3,5-dimethyl-4-methoxymethoxy-2H-pyran-2-one (45 mg), and after stirring the mixture at room temperature for 6 hours, an NH4Cl aqueous solution was added and extraction was performed with CH2Cl2. The organic layer was dried, filtered and concentrated, and the residue was purified by silica gel thin-layer chromatography (CH2Cl2) to obtain 6-(5-acetylamino)benzofuran-2-yl)-3,5-dimethyl-4-methoxymethoxy-2H-pyran-2-one.

Provenance & Evidence