4-Nitrophenol → 2-Bromo-4-nitrophenol

HRID 1357438Notes

Reaction equation

[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[CH:6][CH:5]=1)([O-:3])=[O:2].[Br:11]N1C(=O)CCC1=O>>[Br:11][C:8]1[CH:9]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=[CH:6][C:7]=1[OH:10]

Participants

Reactant 2

HCID 9804-Nitrophenol

HCID 67184N-bromobutanimide

Product 1

HCID 221092-Bromo-4-nitrophenol

Procedure

2-bromo-4-nitrophenol is prepared by reaction of 4-nitrophenol with N-brom-succinimide, according to the paper by T. Oberhouser in J. Org. Chem. 62, pp. 4504 and following (1997).

Sources & evidence

ORD record: ord-d5fe3c58c7ac42b485ab1d2739d7c0fe
Source dataset: uspto-grants-2003_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06592631B2

Reaction notes

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