Oxalyl chloride → HCID 54547380, compound

HRID 1357759Notes

Reaction equation

HRID 1357759 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][C:9]([OH:11])=O)[CH:2]=1.C(Cl)(=O)C(Cl)=O.[O:18]=[C:19]1[N:23]([CH:24]2[CH2:29][CH2:28][N:27]([CH2:30][CH2:31][CH2:32][CH2:33][NH2:34])[CH2:26][CH2:25]2)[C:22]2[CH:35]=[CH:36][CH:37]=[CH:38][C:21]=2[NH:20]1>>[O:18]=[C:19]1[N:23]([CH:24]2[CH2:29][CH2:28][N:27]([CH2:30][CH2:31][CH2:32][CH2:33][NH:34][C:9](=[O:11])[CH:8]=[CH:7][C:3]3[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=3)[CH2:26][CH2:25]2)[C:22]2[CH:35]=[CH:36][CH:37]=[CH:38][C:21]=2[NH:20]1

Participants

4

Reactant 3

HCID 65578Oxalyl chlorideHCID 1019843-(3-Pyridinyl)-2-propenoic acidHCID 18187426HCID 18187426, compound

Product 1

HCID 54547380HCID 54547380, compound

Procedure

Batch size: 1.47 g (9.9 mmol) 3-(3-pyridyl)-acrylic acid, 1.15 ml (13.5 mmol) oxalyl chloride and 2.6 g (9.0 mmol) 4-[4-(2-oxo-2.3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-butylamine.

Sources & evidence

ORD record
ord-d2c3ab05c6e940aa95a770b6180ab244
Source dataset
uspto-grants-2003_07
Patent number
US06593344B1

Reaction notes

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