1,1'-Carbonyldiimidazole → HCID 18187407, compound

HRID 1357763Notes

Reaction equation

HRID 1357763 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][CH2:8][CH2:9][CH2:10][C:11]([OH:13])=O)[CH:2]=1.C1N=CN(C(N2C=NC=C2)=O)C=1.[CH:26]1[C:36]2[C:35](=[C:37]3[CH2:42][CH2:41][N:40]([CH2:43][CH2:44][CH2:45][CH2:46][NH2:47])[CH2:39][CH2:38]3)[C:34]3[CH:48]=[CH:49][CH:50]=[CH:51][C:33]=3[CH2:32][S:31][C:30]=2[CH:29]=[CH:28][CH:27]=1>>[CH:26]1[C:36]2[C:35](=[C:37]3[CH2:38][CH2:39][N:40]([CH2:43][CH2:44][CH2:45][CH2:46][NH:47][C:11](=[O:13])[CH2:10][CH2:9][CH2:8][CH2:7][C:3]4[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=4)[CH2:41][CH2:42]3)[C:34]3[CH:48]=[CH:49][CH:50]=[CH:51][C:33]=3[CH2:32][S:31][C:30]=2[CH:29]=[CH:28][CH:27]=1

Participants

4

Reactant 3

HCID 682631,1'-CarbonyldiimidazoleHCID 114807975-(3-Pyridinyl)pentanoic acidHCID 181874334-[4-(6,11-Dihydro-dibenzo-[b,e]thiepin-11-yliden)-piperidin-1-yl]-butylamine

Product 1

HCID 18187407HCID 18187407, compound

Procedure

Batch size: 1.6 g (9.0 mmol) 5-(3-pyridyl)-pentanic acid, 1.6 g (9.9 mmol) CDI and 3.0 g (8.2 mmol) 4-[4-(6,11-dihydro-dibenzo-[b,e]thiepin-11-yliden)-piperidin-1-yl]-butylamine.

Sources & evidence

ORD record
ord-3b90a0fd9d5b47bd8fbb15a4880a7a53
Source dataset
uspto-grants-2003_07
Patent number
US06593344B1

Reaction notes

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