1,1'-Carbonyldiimidazole → HCID 53766937, compound

HRID 1357765Notes

Reaction equation

HRID 1357765 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][C:9]([OH:11])=O)[CH:2]=1.C1N=CN(C(N2C=NC=C2)=O)C=1.[O:24]1[C:28]2([CH2:33][CH2:32][N:31]([CH2:34][CH2:35][CH2:36][CH2:37][NH2:38])[CH2:30][CH2:29]2)[O:27][CH2:26][CH2:25]1>>[O:27]1[C:28]2([CH2:29][CH2:30][N:31]([CH2:34][CH2:35][CH2:36][CH2:37][NH:38][C:9](=[O:11])[CH:8]=[CH:7][C:3]3[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=3)[CH2:32][CH2:33]2)[O:24][CH2:25][CH2:26]1

Participants

4

Reactant 3

HCID 682631,1'-CarbonyldiimidazoleHCID 1019843-(3-Pyridinyl)-2-propenoic acidHCID 18187436HCID 18187436, compound

Product 1

HCID 53766937HCID 53766937, compound

Procedure

Batch size: 4.0 g (26.8 mmol) 3-(3-pyridyl)-acrylic acid, 5.7 g (35.2 mmol) CDI and 6.4 g (29.9 mmol) 4-(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)-butylamine.

Sources & evidence

ORD record
ord-1d3655e19726400c8873582491bc8804
Source dataset
uspto-grants-2003_07
Patent number
US06593344B1

Reaction notes

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