Ethyl bromoacetate → 4-(5-Methyl-1,2,4-oxadiazol-3-yl)-phenylamino-ethyl acetate

HRID 1357803Notes

Reaction equation

HRID 1357803 reaction equation
[CH3:1][C:2]1[O:6][N:5]=[C:4]([C:7]2[CH:13]=[CH:12][C:10]([NH2:11])=[CH:9][CH:8]=2)[N:3]=1.Br[CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17]>C(N(C(C)C)C(C)C)C>[C:16]([O:18][CH2:19][CH2:20][NH:11][C:10]1[CH:12]=[CH:13][C:7]([C:4]2[N:3]=[C:2]([CH3:1])[O:6][N:5]=2)=[CH:8][CH:9]=1)(=[O:17])[CH3:15]

Participants

4

Reactant 2

HCID 7748Ethyl bromoacetateHCID 181881764-(5-Methyl-1,2,4-oxadiazol-3-yl)aniline

Product 1

HCID 699894414-(5-Methyl-1,2,4-oxadiazol-3-yl)-phenylamino-ethyl acetate

Reagents, catalysts & solvents 1

HCID 81531DiisopropylethylamineSolvent

Procedure

Prepared analogously to Example 1k from 4-(5-methyl-1,2,4-oxadiazol-3-yl)-aniline and ethyl bromoacetate in N-ethyl-diisopropylamine.

Sources & evidence

ORD record
ord-7965e3ec56f3411d9b12dc35741321ed
Source dataset
uspto-grants-2003_07
Patent number
US06593355B2

Reaction notes

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