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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1357900Generated: November 2, 2026

Hydrochloric Acid → HCID 18187862, compound

https://huagongshe.com/reaction/1357900

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 18187735HCID 18187735—
SolventMethanolHCID 887—
ProductHCID 18187862HCID 18187862—

Reaction Steps

A solution of 1-(t-butoxycarbonyl)-4-(3-(quinolin-3-yl)propyl)piperidine from Step A (240 mg, 0.68 mmol) in 1M HCl solution (8 mL) in methanol was stirred at rt for 48 h. The solution was concentrated and the residue crystallized from ethyl acetate to afford the title compound (182 mg),

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06593346B2
Source datasetuspto-grants-2003_07
ORD IDord-1db572ddcdf145499b15b77a67b399ea
Source noteuspto-grants-2003_07