HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 4-(2-Hvdroxyeth-1-yl)piperidine Acetic Acid Salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | 4-Pyridineethanol | HCID 72921 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Product | 4-(2-Hvdroxyeth-1-yl)piperidine Acetic Acid Salt | HCID 18187831 | 100% |
Reaction Steps
Combined 4-(2-hydroxyeth-1-yl)pyridine (25 g, 0.2 mol) and platinum oxide (1 g, 4.4 mmol) in 400 mL acetic acid. Placed under 45 psi hydrogen at 60° C. for 24 h. Decanted, then filtered through Celite and removed the solvent to afford 38 g (100%) of the crude product, which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06593346B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-8ab9c854191949a9877cf8e7d514c978 |
| Source note | uspto-grants-2003_07 |