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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1357991Generated: November 3, 2026

Pyrrolidine, 2-(2-chloroethyl)-1-methyl-, hydrochloride (1:1) → HCID 12070124, compound

https://huagongshe.com/reaction/1357991

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidine, 2-(2-chloroethyl)-1-methyl-, hydrochloride (1:1)HCID 3017050—
ReactantHCID 12070121HCID 12070121—
ProductHCID 12070124HCID 1207012445%

Reaction Steps

The title compound was prepared as described in Example 3.D, using 2-(4-fluorophenyl)-1-(4-hydroxybenzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline (0.13 g, 0.36 mmol) and 2-(2-chloroethyl)-1-methylpyrrolidine hydrochloride (0.079 g, 0.429 mmol) to provide the title compound (0.076 g, 45% yield): ES-MS (m/z) 475 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06593322B1
Source datasetuspto-grants-2003_07
ORD IDord-a2d5d6e6237b4d3abc254ae40e3c905b
Source noteuspto-grants-2003_07