huagongshe.com
HRID1358332

反应详情

EQUATION

反应方程式

HRID 1358332 的结构方程式

REACTANTS

反应物

2
结构：O=S(=O)(Cl)c1cccs1
HCID85518

2-Thiophenesulfonyl chloride

C4H3ClO2S2

结构：CSc1nc(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c(-c2ccccc2)c(OCCN)n1
HCID18184199

未命名化合物

PRODUCTS

生成物

1
结构：NS(=O)(=O)c1ccccc1
HCID7370

Benzenesulfonamide

C6H7NO2S

PROCEDURE

实验过程

According to Example 4a) 100 mg 4-tert.-butyl-N-[6-(2-aminoethoxy)-2-methylsulfanyl-5-phenyl-pyrimidin-4-yl]-benzenesulfonamide was reacted with 121 mg thiophene-2-sulfonylchloride to give 115 mg 4-tert.-butyl-N-[6-(2-(2-thiophenesulfonyl)-amino)-ethoxy)-2-methylsulfanyl-5-phenyl-pydmidin-4-yl]-benzenesulfonamide. LC-MS: tR=5.98 min, [M−1]−=617.39.