HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanesulfonyl chloride → Benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanesulfonyl chloride | HCID 11667 | — |
| Reactant | HCID 18184175 | HCID 18184175 | — |
| Product | Benzenesulfonamide | HCID 7370 | — |
Reaction Steps
According to the procedure described in Example 4a) 200 mg p-tert.-butyl-N-[6-(3-aminopropoxy)-5-(o-methoxyphenoxy)-2-cyclopropyl-4-pyrimidinyl]benzene-sulfonamide was reacted with ethanesulfonylchloride to give 220 mg p-tert.-butyl-N-[6-(3-ethansulfonylamino)-propoxy)-5-(o-methoxyphenoxy)-2-cyclopropyl-4-pyrimidinyl]benzene-sulfonamide. LC-MS: tR=5.74 min, [M+1]+=619.22, [M−1]−=617.24.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06596719B1 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-319ecda79e6e4b9994fc55bc7e426c0a |
| Source note | uspto-grants-2003_07 |