HCID 18184777, compound → HCID 18184759, compound

HRID 1358378Notes

Reaction equation

HRID 1358378 reaction equation
[CH3:1][C:2]1([CH3:20])[CH2:7][C:6]([CH3:9])([CH3:8])[CH2:5][CH:4]([O:10][C:11]2[CH:16]=[CH:15][C:14]([N+:17]([O-])=O)=[CH:13][CH:12]=2)[CH2:3]1.[H][H]>CO.[Pt](=O)=O>[CH3:8][C:6]1([CH3:9])[CH2:7][C:2]([CH3:1])([CH3:20])[CH2:3][CH:4]([O:10][C:11]2[CH:12]=[CH:13][C:14]([NH2:17])=[CH:15][CH:16]=2)[CH2:5]1

Participants

5

Reactant 2

HCID 18184777HCID 18184777, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 18184759HCID 18184759, compound

Reagents, catalysts & solvents 2

HCID 345198Adams' catalystCatalystHCID 887MethanolSolvent

Procedure

Under atmospheric pressure, 8.3 g of 4-(3,3,5,5-tetramethylcyclohexyloxy) nitrobenzene in 500 ml of methanol are hydrogenated in the presence of 400 mg of platinum dioxide until the uptake of hydrogen has ended. The catalyst is filtered off, the solution is then concentrated using a rotary evaporator and the residue, a brownish oil which slowly solidifies, is used for the further reactions without any further purification.

Workup

  1. filtrationThe catalyst is filtered off
  2. concentrationthe solution is then concentrated
  3. customa rotary evaporator
  4. customis used for the further reactions without any further purification

Sources & evidence

ORD record
ord-5287a40b635e4555aba390b17b6b43cb
Source dataset
uspto-grants-2003_07
Patent number
US06596742B1

Reaction notes

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