2,2-Diphenylacetyl chloride → N-(5-Cyclopropyl-[1,3,4]oxadiazol-2-yl)-2,2-diphenyl-acetamide

HRID 1358438Notes

Reaction equation

HRID 1358438 reaction equation
[C:1]1([CH:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:8](Cl)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:17]1([C:20]2[O:24][C:23]([NH2:25])=[N:22][N:21]=2)[CH2:19][CH2:18]1>>[CH:17]1([C:20]2[O:24][C:23]([NH:25][C:8](=[O:9])[CH:7]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)[C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)=[N:22][N:21]=2)[CH2:19][CH2:18]1

Participants

3

Reactant 2

HCID 746372,2-Diphenylacetyl chlorideHCID 167677875-Cyclopropyl-1,3,4-oxadiazol-2-amine

Product 1

HCID 22661086N-(5-Cyclopropyl-[1,3,4]oxadiazol-2-yl)-2,2-diphenyl-acetamide

Procedure

The title compound, white solid, m.p. 159-160° C. and MS: m/e=320.3 (M+H+) was prepared in accordance with the general method of example 44a from 2,2-diphenylacetic acid chloride and 5-cyclopropyl-[1,3,4]oxadiazol-2-ylamine.

Sources & evidence

ORD record
ord-0e0c56b75b6b436aa3103984e01568a4
Source dataset
uspto-grants-2003_07
Patent number
US06596743B2

Reaction notes

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