HCID 87924367, compound → HCID 87924368, compound

HRID 1358741Notes

Reaction equation

HRID 1358741 reaction equation
[F:1][C:2]([F:24])([F:23])[S:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]#[C:11][C:12]2[CH:17]=[CH:16][C:15]([S:18][C:19]([F:22])([F:21])[F:20])=[CH:14][CH:13]=2)=[CH:6][CH:5]=1>[Pd].CCCCCC>[F:21][C:19]([F:20])([F:22])[S:18][C:15]1[CH:14]=[CH:13][C:12]([CH2:11][CH2:10][C:7]2[CH:8]=[CH:9][C:4]([S:3][C:2]([F:24])([F:23])[F:1])=[CH:5][CH:6]=2)=[CH:17][CH:16]=1

Participants

4

Reactant 1

HCID 87924367HCID 87924367, compound

Product 1

HCID 87924368HCID 87924368, compoundYield 103.6%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8058HexaneSolvent

Procedure

1,2-bis(4-trifluoromethylthiophenyl)acetylene (200 mg, 0.53 mmol) was hydrogenated over 10% palladium on carbon (20 mg) in hexane (30 mL) at rt for 2 hours. The reaction was filtered and the filtrate was concentrated to give 0.21 g (100%) of 1,2-bis(4-trifluoromethylthiophenyl)ethane. 1HNMR (360 MHz, DMSO-d6) δ 7.61 (d, J=8.3 Hz, 4H), 7.40 (d, J=8.3 Hz, 4H), 2.97 (s, 4H, CH2CH2). MS-EI m/z 382 [M+].

Workup

  1. filtrationThe reaction was filtered
  2. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-1f777233c49b4d16a029c9e58d97e016
Source dataset
uspto-grants-2003_07
Patent number
US06596772B1

Reaction notes

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