m-Chloroperbenzoic acid → HCID 21138136, compound

HRID 1358885Notes

Reaction equation

HRID 1358885 reaction equation
[CH:1]1([O:6][C:7]2[CH:24]=[CH:23][C:22]3[C@@H:21]4[C@H:12]([C@H:13]5[C@@:17]([CH2:19][C@@H:20]4[C:25]4[CH:30]=[CH:29][C:28]([O:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][S:37]([CH2:39][CH2:40][CH2:41][C:42]([F:48])([F:47])[C:43]([F:46])([F:45])[F:44])=[O:38])=[CH:27][CH:26]=4)([CH3:18])[C@@H:16]([OH:49])[CH2:15][CH2:14]5)[CH2:11][CH2:10][C:9]=3[CH:8]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1.ClC1C=CC=C(C(OO)=[O:58])C=1>>[CH:1]1([O:6][C:7]2[CH:24]=[CH:23][C:22]3[C@@H:21]4[C@H:12]([C@H:13]5[C@@:17]([CH2:19][C@@H:20]4[C:25]4[CH:30]=[CH:29][C:28]([O:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][S:37]([CH2:39][CH2:40][CH2:41][C:42]([F:47])([F:48])[C:43]([F:44])([F:45])[F:46])(=[O:58])=[O:38])=[CH:27][CH:26]=4)([CH3:18])[C@@H:16]([OH:49])[CH2:15][CH2:14]5)[CH2:11][CH2:10][C:9]=3[CH:8]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 21138134HCID 21138134, compound

Product 1

HCID 21138136HCID 21138136, compoundYield 79.4%

Procedure

By operating as in Example 56 using at the start 698 mg of the product obtained in Example 68 and 228 mg of metachloro perbenzoic acid, 567 mg of expected product is obtained. M.p.=166° C.

Sources & evidence

ORD record
ord-1fdcf838168e49f5874e184935189e78
Source dataset
uspto-grants-2003_07
Patent number
US06596885B2

Reaction notes

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