HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → [4-(4-Methoxy-7-morpholin-4-yl-benzothiazol-2-ylcarbamoyl)-2-oxo-2H-pyridin-1-yl]-acetic Acid Ethyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | 2-Methoxy-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-isonicotinamide | HCID 10194294 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | [4-(4-Methoxy-7-morpholin-4-yl-benzothiazol-2-ylcarbamoyl)-2-oxo-2H-pyridin-1-yl]-acetic Acid Ethyl Ester | HCID 10238755 | — |
Reaction Steps
From 2-methoxy-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-isonicotinamide with sodium iodide and ethyl bromoacetate in DMF. ES-MS m/e (%): 495 (M+Na+, 25), 473 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06599901B1 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-bd8f81ed8f2b4bbe8080250651fe07ce |
| Source note | uspto-grants-2003_07 |