Isobutyryl chloride → HCID 18180220, compound

HRID 1358978Notes

Reaction equation

[NH2:1][C:2]1[C:7]([C:8]2[CH:13]=[C:12]([Cl:14])[CH:11]=[C:10]([Cl:15])[C:9]=2[Cl:16])=[N:6][CH:5]=[C:4]([NH:17][C:18](=[O:20])[CH3:19])[N:3]=1.[C:21](Cl)(=[O:25])[CH:22]([CH3:24])[CH3:23]>>[CH:22]([C:21]([NH:1][C:2]1[C:7]([C:8]2[CH:13]=[C:12]([Cl:14])[CH:11]=[C:10]([Cl:15])[C:9]=2[Cl:16])=[N:6][CH:5]=[C:4]([NH:17][C:18](=[O:20])[CH3:19])[N:3]=1)=[O:25])([CH3:24])[CH3:23]

Participants

Reactant 2

HCID 62325Isobutyryl chloride

HCID 18180219HCID 18180219, compound

Product 1

HCID 18180220HCID 18180220, compound

Procedure

This compound was prepared in an analogous manner to Example 9 from 2-amino-6-acetamido-3(2,3,5-trichlorophenyl)pyrazine (Example 1) and one equivalent isobutyrylchloride (Aldrich). Yield 0.120 g M.p. 230-232° C.

Sources & evidence

ORD record: ord-9658d7ea2fa74d6f83767bb89ccffd35
Source dataset: uspto-grants-2003_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06599905B2

Reaction notes

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