Dimethylformamide diethylacetal → HCID 54176307, compound

HRID 1359014Notes

Reaction equation

HRID 1359014 reaction equation
[CH2:1]([O:8][C:9]1[CH:18]=[C:17]2[C:12]([CH2:13][CH2:14][CH2:15][C:16]2=[O:19])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(O[CH:23](OCC)[N:24]([CH3:26])[CH3:25])C>>[CH2:1]([O:8][C:9]1[CH:18]=[C:17]2[C:12]([CH2:13][CH2:14][C:15](=[CH:23][N:24]([CH3:26])[CH3:25])[C:16]2=[O:19])=[CH:11][CH:10]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 70913Dimethylformamide diethylacetalHCID 140682207-(Benzyloxy)-3,4-dihydronaphthalen-1(2H)-one

Product 1

HCID 54176307HCID 54176307, compound

Procedure

7-Benzyloxy-3,4-dihydro-2-dimethylaminomethylene-1(2H)naphthalenone was prepared from 7-benzyloxy-3,4-dihydro-1(2H)naphthalenone (6.0 g, 23.8 mmol) and N,N-dimethylformamide diethylacetal (20 ml, 119.4 mmol) to give the desired compound as a pale yellow solid (4.56 g) m.p. 85-86°. MS(ES+) 308 (MH+, 100%).

Sources & evidence

ORD record
ord-80cec0a8b20c4496b3ec0c5454294acc
Source dataset
uspto-grants-2003_07
Patent number
US06599908B1

Reaction notes

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