Hydrogen Bromide → HCID 178515815, compound

Participants

Reaction Steps

A mixture of 72.5 g of 2-benzyl-3-bromo-6-methoxypyridine and 300 ml of 47% hydrobromic acid was heated under stirring for 4 hours in an oil bath kept at 100° C. After cooling as it was, 500 ml of water was added thereto. The resulting crystals were collected by filtration, washed with water and diethyl ether, air-dried and then dried under heating under reduced pressure, to give 63.8 g of the target compound.

Provenance & Evidence