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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1359288Generated: November 1, 2026

D-Tartaric acid → (3S)-3-ethynyl-1-azabicyclo[2.2.2]octan-3-ol

https://huagongshe.com/reaction/1359288

Reaction equation

Participants

RoleNameHCIDCharge
ReactantD-Tartaric acidHCID 439655—
Reactant3-Ethynyl-1-azabicyclo[2.2.2]octan-3-olHCID 3613517—
Product(3S)-3-ethynyl-1-azabicyclo[2.2.2]octan-3-olHCID 946096—

Reaction Steps

The title compound was synthesized from 3-ethynyl-3-quinuclidinol in the same manner as in Production Example 29 using D-(−)-tartaric acid was used as an optical resolution agent.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06599917B1
Source datasetuspto-grants-2003_07
ORD IDord-9ba37fcd0e4248a9903411ba50ae8301
Source noteuspto-grants-2003_07