D-Tartaric acid → HCID 946096, compound

HRID 1359288Notes

Reaction equation

HRID 1359288 reaction equation
[C:1]([C:3]1([OH:11])[CH:8]2[CH2:9][CH2:10][N:5]([CH2:6][CH2:7]2)[CH2:4]1)#[CH:2].C(O)(=O)[C@H]([C@@H](C(O)=O)O)O>>[C:1]([C@@:3]1([OH:11])[CH:8]2[CH2:9][CH2:10][N:5]([CH2:6][CH2:7]2)[CH2:4]1)#[CH:2]

Participants

3

Reactant 2

HCID 439655D-Tartaric acidHCID 36135173-Ethynyl-1-azabicyclo[2.2.2]octan-3-ol

Product 1

HCID 946096HCID 946096, compound

Procedure

The title compound was synthesized from 3-ethynyl-3-quinuclidinol in the same manner as in Production Example 29 using D-(−)-tartaric acid was used as an optical resolution agent.

Sources & evidence

ORD record
ord-9ba37fcd0e4248a9903411ba50ae8301
Source dataset
uspto-grants-2003_07
Patent number
US06599917B1

Reaction notes

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