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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1359696Generated: October 25, 2026

5-(2,6-Dichloro-phenylmethanesulfonyl)-1,3-dihydro-indol-2-one → 5-(2,6-Dichloro-phenylmethanesulfonyl)-3-[1-(3,5-dimethyl-4-morpholin-4-ylmethyl-1h-pyrrol-2-yl)-meth-(z)-ylidene]-1,3-dihydro-indol-2-one

https://huagongshe.com/reaction/1359696

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(2,6-Dichloro-phenylmethanesulfonyl)-1,3-dihydro-indol-2-oneHCID 18179768—
Reactant3,5-dimethyl-4-morpholin-4-ylmethyl-1H-pyrrole-2-carbaldehydeHCID 22059717—
Product5-(2,6-Dichloro-phenylmethanesulfonyl)-3-[1-(3,5-dimethyl-4-morpholin-4-ylmethyl-1h-pyrrol-2-yl)-meth-(z)-ylidene]-1,3-dihydro-indol-2-oneHCID 59077617—

Reaction Steps

5-(2,6-Dichlorophenylmethanesulfonyl)-1,3-dihydro-indol-2-one was condensed with 3,5-dimethyl-4-morpholin-4-ylmethyl-1H-pyrrole-2-carbaldehyde to give 2.0 g of the titled compound as an orange solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06599902B2
Source datasetuspto-grants-2003_07
ORD IDord-b5ee9c0f28ad48289721a2d61288b607
Source noteuspto-grants-2003_07