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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1359747Generated: October 27, 2026

(S)-2-cyclopropylcarbamoyl-pyrrolidine-1-carboxylic acid benzyl ester → (2S)-N-Cyclopropylpyrrolidine-2-carboxamide

https://huagongshe.com/reaction/1359747

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-cyclopropylcarbamoyl-pyrrolidine-1-carboxylic acid benzyl esterHCID 69997288—
CatalystPalladiumHCID 23938—
Product(2S)-N-Cyclopropylpyrrolidine-2-carboxamideHCID 22691330—

Reaction Steps

(S)-2-cyclopropylcarbamoyl-pyrrolidine-1-carboxylic acid benzyl ester (907 mg, 3.14 mmol) was hydrogenated using Pd/C (5%, 61 mg) to give (S)-pyrrolidine-2-carboxylic acid cyclopropylamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06599902B2
Source datasetuspto-grants-2003_07
ORD IDord-33741e3476b649c0ba109edaa47a2e26
Source noteuspto-grants-2003_07