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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1359763Generated: November 3, 2026

5-(2,6-Dichloro-phenylmethanesulfonyl)-1,3-dihydro-indol-2-one → HCID 59077570, compound

https://huagongshe.com/reaction/1359763

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(2,6-Dichloro-phenylmethanesulfonyl)-1,3-dihydro-indol-2-oneHCID 18179768—
ReactantHCID 88094453HCID 88094453—
SolventEthanolHCID 702—
SolventPiperidineHCID 8082—
ProductHCID 59077570HCID 59077570—

Reaction Steps

5-(2,6-Dichloro-phenylmethanesulfonyl)-1,3-dihydro-indol-2-one was condensed with 4-((R)-3-hydroxy-pyrrolidin-1-ylmethyl)-3,5-dimethyl-1H-pyrrole-2-carbaldehyde in ethanol and piperidine to give the titled compound as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06599902B2
Source datasetuspto-grants-2003_07
ORD IDord-c89e676b1a1443bd88fdc9bf56536ff6
Source noteuspto-grants-2003_07