HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18179750, compound → HCID 59077551, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18179750 | HCID 18179750 | — |
| Reactant | 5-(2,6-Dichloro-phenylmethanesulfonyl)-1,3-dihydro-indol-2-one | HCID 18179768 | — |
| Catalyst | Piperidine | HCID 8082 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 59077551 | HCID 59077551 | — |
Reaction Steps
5-(2,6-Dichloro-phenylmethanesulfonyl)-1,3-dihydro-indol-2-one (357 mg, 1 mmol) was condensed with 4-(4-acetyl-piperazin-1-ylmethyl)-3,5-dimethyl-1H-pyrrole-2-carbaldehyde (263 mg, 1 mmol) in ethanol (3 mL) and piperidine (3 drops) at 95-100° C. for 2 hours to give the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06599902B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-d875abf9856648e69c45213096ba143f |
| Source note | uspto-grants-2003_07 |