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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1359876Generated: November 2, 2026

1-[4-(2-Aminoethyl)piperazin-1-yl]ethan-1-one → N-[2-(4-Acetyl-piperazin-1-yl)-ethyl]-2-{5-[5-(2,6-dichloro-phenylmethanesulfonyl)-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrol-3-yl}-acetamide

https://huagongshe.com/reaction/1359876

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[4-(2-Aminoethyl)piperazin-1-yl]ethan-1-oneHCID 16785703—
ReactantHCID 59077497HCID 59077497—
ProductN-[2-(4-Acetyl-piperazin-1-yl)-ethyl]-2-{5-[5-(2,6-dichloro-phenylmethanesulfonyl)-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrol-3-yl}-acetamideHCID 59077649—

Reaction Steps

{5-[5-(2,6-dichloro-phenylmethanesulfonyl)-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrol-3-yl}-acetic acid was coupled with 1-[4-(2-amino-ethyl)-piperazin-1-yl]-ethanone to give the titled compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06599902B2
Source datasetuspto-grants-2003_07
ORD IDord-711d1ca965114bdd8f2fcc37745aba9b
Source noteuspto-grants-2003_07