Triethylamine → rac-(2'S,3'S,4'S)-6-chloro-2'-(3-chloro-2-fluoro-phenyl)-4'-(2,2-dimethyl-propyl)-2-oxo-1,2-dihydro-spiro[indole-3,3'-pyrrolidine]-1'-carboxylic acid (1-methyl-1H-pyrazol-3-ylmethyl)-amide
Reaction equation
[CH3:32][n:33]1[n:34][c:35]([CH2:38][NH2:39])[cH:36][cH:37]1.[CH3:40][CH2:41][N:42]([CH2:43][CH3:44])[CH2:45][CH3:46].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[C:6]21[CH:12]([c:24]2[c:25]([F:31])[c:26]([Cl:30])[cH:27][cH:28][cH:29]2)[N:13]([C:21](=[O:22])[Cl:23])[CH2:14][CH:15]1[CH2:16][C:17]([CH3:18])([CH3:19])[CH3:20]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[C:6]21[CH:12]([c:24]2[c:25]([F:31])[c:26]([Cl:30])[cH:27][cH:28][cH:29]2)[N:13]([C:21](=[O:22])[NH:39][CH2:38][c:35]2[n:34][n:33]([CH3:32])[cH:37][cH:36]2)[CH2:14][CH:15]1[CH2:16][C:17]([CH3:18])([CH3:19])[CH3:20]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-199f94224aaf47b49386b72f2f966cd1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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