HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 4-[(Methylamino)methyl]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 4-(Bromomethyl)benzoic acid | HCID 22599 | — |
| Product | 4-[(Methylamino)methyl]benzoic acid | HCID 13922254 | — |
Reaction Steps
4-Bromomethyl-benzoic acid (5 g, 22.8 mmol) is treated with a methylamine solution (40%, 75 mL, 867 mmol) for 4 days at ambient temperature. The resulting mixture is evaporated and the residue purified by flash chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07879853B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-1ea9e60901ea41a9a6363976d7ace138 |
| Source note | uspto-grants-2011_02 |