Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | HCID 86087217 | HCID 86087217 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 66963342 | HCID 66963342 | — |
Reaction Steps
Ethyl 4-(1-formylamino-1-methyl-ethyl)-benzoate (2.97 g, 12.6 mmol) is added to a mixture of water (30 mL), dioxane (15 mL) and concentrated hydrochloric acid (3.01 mL, 36.1 mmol) and the mixture is heated to 100° C. for 12 h. The reaction mixture is evaporated and the residue is crystallized from ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07879853B2 |
|---|
| Source dataset | uspto-grants-2011_02 |
|---|
| ORD ID | ord-325229a10af0495fabd1b0c27a63e632 |
|---|
| Source note | uspto-grants-2011_02 |
|---|
