HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 5-carbamoylpyridine-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 5-[(Benzyloxy)carbonyl]pyridine-3-carboxylate | HCID 71353015 | — |
| Product | 5-carbamoylpyridine-3-carboxylic acid | HCID 336682 | — |
Reaction Steps
Monobenzyl pyridine-3,5-dicarboxylate (compound G2) (1.92 g, 7.5 mmol) is heated in aqueous concentrated ammonia solution (40 mL, 25%) to 90° C. for 6 h. After cooling, the solution is evaporated and the residue is used as crude product without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07879853B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-c4c7447aed4642a98694c1bb33a1f2bd |
| Source note | uspto-grants-2011_02 |