HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 6-Carbamoylpyridine-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 2,6-Pyridinedicarboxylic acid, mono(phenylmethyl) ester | HCID 71340367 | — |
| Product | 6-Carbamoylpyridine-2-carboxylic acid | HCID 18676698 | — |
Reaction Steps
Monobenzyl pyridine-2,6-dicarboxylate (compound H1) (1 g, 3.8 mmol) and aqueous 25-% ammonia solution (40 mL) are heated to 90° C. for 6 h. After cooling the mixture is evaporated and washed with ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07879853B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-93ad077b52224cf3aee5feab256b15d1 |
| Source note | uspto-grants-2011_02 |