Tetrahydrofuran → N-[2-chloro-5-(1-hydroxy-ethyl)-phenyl]-3,4-dimethoxy-benzenesulfonamide

HRID 136042Notes

Reaction equation

HRID 136042 reaction equation
[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:24][Li:25].[Cl:1][c:2]1[c:3]([NH:10][S:11](=[O:12])(=[O:13])[c:14]2[cH:15][c:16]([O:22][CH3:23])[c:17]([O:20][CH3:21])[cH:18][cH:19]2)[cH:4][c:5]([CH:8]=[O:9])[cH:6][cH:7]1>>[Cl:1][c:2]1[c:3]([NH:10][S:11](=[O:12])(=[O:13])[c:14]2[cH:15][c:16]([O:22][CH3:23])[c:17]([O:20][CH3:21])[cH:18][cH:19]2)[cH:4][c:5]([CH:8]([OH:9])[CH3:24])[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 57511304N-(2-chloro-5-formyl-phenyl)-3,4-dimethoxy-benzenesulfonamideHCID 178418348HCID 178418348, compound

Product 1

HCID 57511305N-[2-chloro-5-(1-hydroxy-ethyl)-phenyl]-3,4-dimethoxy-benzenesulfonamide

Sources & evidence

ORD record
ord-534a2668fa1b4dc5b919ecbe7052d642
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…