tert-Butylhydrazine monohydrochloride → HCID 66958342, compound

HRID 1360449Notes

Reaction equation

HRID 1360449 reaction equation
[CH2:1]([O:3][C:4](=[O:14])[C:5](=O)[CH:6]=[C:7]([O-])[CH2:8][CH2:9][CH2:10][CH3:11])[CH3:2].[Na].Cl.[C:17]([NH:21][NH2:22])([CH3:20])([CH3:19])[CH3:18]>>[CH2:8]([C:7]1[N:21]([C:17]([CH3:20])([CH3:19])[CH3:18])[N:22]=[C:5]([C:4]([O:3][CH2:1][CH3:2])=[O:14])[CH:6]=1)[CH2:9][CH2:10][CH3:11]

Participants

4

Reactant 3

HCID 81889tert-Butylhydrazine monohydrochlorideHCID 5360545SodiumHCID 178447100HCID 178447100, compound

Product 1

HCID 66958342HCID 66958342, compound

Procedure

1-Ethoxy-1,2-dioxooct-3-en-4-olate, sodium salt (332.8 g, 1.50 mol) was treated with tert-butylhydrazine hydrochloride (186.6 g, 1.50 mol) according to the procedure described in Part B of Examples 37-39 to yield ethyl 5-butyl-1-tert-butyl-1H-pyrazole-3-carboxylate as a brown oil.

Sources & evidence

ORD record
ord-1ff3830d43494cefb701e85c2c59385f
Source dataset
uspto-grants-2011_02
Patent number
US07879849B2

Reaction notes

Loading…