Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2,4,5-Trifluorobenzoyl chloride | HCID 145164 | — |
| Reactant | Ethyl 3-(cyclopentylamino)buta-2-enoate | HCID 66962611 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 178472172 | HCID 178472172 | — |
Reaction Steps
Under ice cooling, triethylamine and 2,4,5-trifluorobenzoyl chloride were added to a solution of ethyl 3-(cyclopentylamino)buta-2-enoate in dioxane, for stirring at ambient temperature for 30 minutes and at 65° C. for one hour, to obtain ethyl 3-(cyclopentylamino)-2-(2,4,5-trifluorobenzoyl)buta-2-enoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07879878B2 |
|---|
| Source dataset | uspto-grants-2011_02 |
|---|
| ORD ID | ord-df21facae4124dc9a58d3d1110403fd7 |
|---|
| Source note | uspto-grants-2011_02 |
|---|
