Hydrazine hydrate (1:1) → HCID 86023618, compound

HRID 1360659Notes

Reaction equation

HRID 1360659 reaction equation
O.NN.[CH2:4]([O:6][P:7]([C:12]([F:26])([F:25])[CH2:13][N:14]1C(=O)C2C(=CC=CC=2)C1=O)(=[O:11])[O:8][CH2:9][CH3:10])[CH3:5]>C(Cl)Cl>[CH2:4]([O:6][P:7]([C:12]([F:26])([F:25])[CH2:13][NH2:14])(=[O:11])[O:8][CH2:9][CH3:10])[CH3:5]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 86606190HCID 86606190, compound

Product 1

HCID 86023618HCID 86023618, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Hydrazine monohydrate was added to a methylene chloride solution of diethyl[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1,1-difluoroethyl]phosphonate, for stirring at ambient temperature for one hour, to obtain diethyl(2-amino-1,1-difluoroethyl)phosphonate.

Sources & evidence

ORD record
ord-0a7d31811520469faa433cd63f5549fd
Source dataset
uspto-grants-2011_02
Patent number
US07879878B2

Reaction notes

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