Hydrochloric Acid → HCID 86023621, compound

HRID 1360662Notes

Reaction equation

HRID 1360662 reaction equation
Cl.[CH2:2]([O:4][P:5]([CH:10]([C:18]#[N:19])[CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)(=[O:9])[O:6][CH2:7][CH3:8])[CH3:3]>CCO.[Pt]=O>[CH2:7]([O:6][P:5]([CH:10]([CH2:11][CH:12]1[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]1)[CH2:18][NH2:19])(=[O:9])[O:4][CH2:2][CH3:3])[CH3:8]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 281202diethyl(1-cyano-2-phenylethyl)phosphonate

Product 1

HCID 86023621HCID 86023621, compound

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 702EthanolSolvent

Procedure

Platinum oxide and conc.HCl were added to a solution of diethyl(1-cyano-2-phenylethyl)phosphonate in EtOH, for overnight stirring under hydrogen atmosphere, to obtain diethyl[2-amino-1-(cyclohexylmethyl)ethyl]phosphonate.

Sources & evidence

ORD record
ord-76adf9ca432c40cb9664bf868359f583
Source dataset
uspto-grants-2011_02
Patent number
US07879878B2

Reaction notes

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