HCID 57700380, compound → HCID 57700381, compound

Participants

Reaction Steps

A solution of 1-(6-chloropyridin-2-yl)-1-(2,6-dichlorophenyl)but-3-yn-2-one (Step A above, 102 mg) in pyridine (7 mL) was heated to 90° C. for about 1½ hr and cooled to room temperature. The mixture was evaporated and purified by silica gel (methylene chloride/acetone=3/1) to give desired product as a yellowish solid (90 mg).

Provenance & Evidence