Thiazolidinedione → HCID 75317588, compound

HRID 1360992Notes

Reaction equation

[CH2:1](Br)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:9][C:10]1[NH:11][C:12]2[C:17]([C:18]=1[CH:19]=O)=[CH:16][CH:15]=[CH:14][CH:13]=2.[S:21]1[CH2:25][C:24](=[O:26])[NH:23][C:22]1=[O:27]>>[CH2:1]([N:11]1[C:12]2[C:17](=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:18]([CH:19]=[C:25]2[S:21][C:22](=[O:27])[NH:23][C:24]2=[O:26])=[C:10]1[CH3:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 3

HCID 5437Thiazolidinedione

HCID 7498Benzyl Bromide

HCID 731663-Formyl-2-methylindole

Product 1

HCID 75317588HCID 75317588, compound

Procedure

This compound was prepared in analogy with the compound described in example 200 from benzyl bromide and 2-methylindole-3-carbaldehyde, followed by reaction with thiazolidine-2,4-dione resulting in 50 mg of the title compound.

Workup

customThis compound was prepared in analogy with the compound

Sources & evidence

ORD record: ord-c04ecba458f6451e8dc4ddac12a26f97
Source dataset: uspto-grants-2011_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07879893B2

Reaction notes

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