Methanol → 4-(1,1-Dimethylethyl) 1-(phenylmethyl) 2-(hydroxymethyl)-1,4-piperazinedicarboxylate

HRID 136106Notes

Reaction equation

HRID 136106 reaction equation
[BH3:27].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH:12]([C:24](=[O:25])[OH:26])[CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]1.[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:28][OH:29]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH:12]([CH2:24][OH:25])[CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]1

Participants

5

Reactant 4

HCID 887MethanolHCID 6331BoraneHCID 8028TetrahydrofuranHCID 2756777N-4-Boc-N-1-Cbz-2-piperazine carboxylic acid

Product 1

HCID 235310394-(1,1-Dimethylethyl) 1-(phenylmethyl) 2-(hydroxymethyl)-1,4-piperazinedicarboxylate

Sources & evidence

ORD record
ord-9f03bb125ed84c2d98fd126d0db13679
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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